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Image Search Results
Journal: bioRxiv
Article Title: Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind
doi: 10.1101/2024.09.16.613237
Figure Lengend Snippet: ( a ) Schematic showing ChrimsonR expression in dopamine terminals, and dLight1.3b expression in the NAc core. ( b to c ) Dopamine response to different pulse numbers (0, 5, 10, 15, or 20; 589 nm, 20 Hz) in offer-sensitive (b) and offer-insensitive (c), highlighting calibrated stimulation parameters. ( d ) Offer zone locations (red shading and text) where optogenetic stimulation was delivered on half of offers > 15 s. ( e ) zIdPhi on trials without (No Stim) and with light delivery (Stim) at less preferred flavors. ( f ) Change in zIdPhi caused by light delivery at less preferred flavors. ( g ) Schematic showing behavior in the wait zone after light delivery in the offer zone (dotted red line) had ended. ( h ) Probability of quitting on trials after no light delivery (No Stim) or light delivery (Stim) at less preferred flavors. ( i ) Change in probability of quitting caused by light delivery at less preferred flavors. Data are mean +/- SEM for all panels; open and filled circles represent female and male mice, respectively. *p<0.05, **p<0.01, simple effect of light delivery (e and h) or offer sensitivity (f and i); complete statistics are provided in Supplementary Tables.
Article Snippet: An
Techniques: Expressing
Journal: bioRxiv
Article Title: Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind
doi: 10.1101/2024.09.16.613237
Figure Lengend Snippet: (a to b) Optogenetic stimulation-response curves for each offer-sensitive (a) and offer-insensitive (b) mouse using the following parameters: pulse number 0, 5, 10, 15, or 20; wavelength 589 nm; frequency 20 Hz. (c) Stimulation parameters did not differ on average between offer-sensitive and offer-insensitive mice. (d) Average total number of pulses delivered in the offer zone for each trial did not differ (n=6/10 for offer-sensitive/insensitive). Data are mean +/- SEM for all panels; open and filled circles represent female and male mice, respectively. Complete statistics are provided in Supplementary Tables.
Article Snippet: An
Techniques: